Flow-Through Cell Apparatus (USP Apparatus 4): Operation and Features
نویسندگان
چکیده
منابع مشابه
Suppository Dissolution Utilizing USP Apparatus
Standardized in-vitro dissolution testing of suppositories has been of interest to the pharmaceutical industry since the early works of Giabaldi and Gundhofer in 1975.(1) Anthony Palmieri exam ined standard izin g suppository dissolutions in his work at the University of Wyoming (2). Palmieri developed a slotted dissolution basket for suppositories that is ---------widely used by many individua...
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USP dissolution Apparatus 4 can have a pulsing or non-pulsing flow, with most commercial apparatus employing a pulsing flow. Overall, a low velocity flow field is present, particularly in the larger 22.6-mm diameter cell. Dissolution data, computational fluid dynamics (CFD), and imaging methods are used and discussed to investigate the effects of low velocity pulsing flow on dissolution. Local ...
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This report summarizes some trends observed in drug dissolution testing, based upon the United States Pharmacopeia (USP) dissolution Apparatus Suitability Test results and the preliminary data obtained from an international collaborative study to assess the pharmaceutical quality of furosemide products in different countries. Based on the USP calibrator data submitted by the participants, repre...
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Introduction Soft gelatin capsule (SGC) formulations are becoming more popular in recent years (1,2). These formulations can mask odors and unpleasant tastes,and are easy to swallow. They are suitable for encapsulation of lipid solutions,suspensions,or paste-like formulations,making them a useful option when formulating poorly water-soluble drugs. Due to the unique properties of SGC formulation...
متن کاملExperimental and Computational Study on Hydrodynamic of a Downscaled Mini Vessel USP Dissolution Test Apparatus II
Although not listed on the United States Pharmacopeia (USP), like standard USP 2, small volume USP 2 dissolution apparatus has gained a great deal of attention, especially for cases where small amount of drug product is available for testing in research and design step or evaluations are to be made on a tablet containing trace amounts of the active pharmaceutical ingredient. In this work, first...
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ژورنال
عنوان ژورنال: Dissolution Technologies
سال: 2011
ISSN: 1521-298X
DOI: 10.14227/dt180411p46